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E87085
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上消化道症狀、心理社會因素與幽門螺旋桿菌感染在消化性潰瘍中之相互關係之探討
The Relationship among Dyspepsia, Psychosocial Factors and Helicobacter Pylori Infection in Peptic Ulcer Disease
1.梁繼權
1.Kai-kuen Leung
1.國立臺灣大學附設醫院家庭醫學科
1.Department of Family Medicine, National Taiwan University Hospital
001,002,003,004
1.國立臺灣大學附設醫院家庭醫學科
1.Department of Family Medicine, National Taiwan University Hospital
002
1.行政院國家科學委員會
1.National Science Council
A.14 計畫執行期間(起):1997-08-01
A.14 計畫執行期間(訖):1998-07-31
A.16 收到日期:1999-07-27
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台大醫院家庭醫學部門診、健康檢查病房及胃腸科門診病人及正常人

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C.2 聯絡日期:1999-07-27
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1.國立臺灣大學附設醫院家庭醫學科
1.Department of Family Medicine, National Taiwan University Hospital
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C.7 資料公開日期:2000-08-01
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1.上消化道症狀
2.心理社會因素
3.幽門螺旋桿菌
4.消化性潰瘍
1.Dyspepsia
2.Helicobacter Pylori
3.Peptic Ulcer
4.Psychosocial Factor
消化道疾病的發生與心理社會因素的關係一直是一個難以釐清的問題。近年來,幽門螺旋菌的發生使興化性潰瘍在病因探討與治療上獲得突破的發展,但幽門螺旋菌感 染與心理社會因素的關係仍然沒有進一步的研究與了解本研究將以壓力模式收集心理社會因素資料及幽門螺旋菌感染,上消化道症狀等資料,以了解三者在消化性潰 瘍中扮演的角色與關係,並計畫長期追蹤以了解心理社會因素及幽門螺旋菌感染的變化對疾病及症狀的影響。第一年的研究共收集88位個案,包括有症狀的急性消 化性潰瘍病人,無症狀潰瘍病人,及正常人。初步測試本研究工具,上消化道症狀問卷、簡式症狀量表、最近生活經驗調查量表及病人自填性格量表。結果顯示上消 化道症狀問卷可以分為四個因素﹐可以解釋52.1%的變異量。本問卷整體的內部一致性檢定a值為0.65。簡式症狀量各分量表之 a值約介於0.5-0.7 之間。病人自填性格量表(MPI)之 Neurotism分量表 a值為0.79﹐extroversion 分量表 a值為0.71。消化道症狀以上腹痛及腹脹為最多。在有症狀的病人中有幽門螺旋桿菌感染率為 92.5%,在無症狀無消化性潰瘍者幽門螺旋桿菌感染率為50.0%。

How psychosocial factors affect the occurrence of gastrointestinal disorder is a unresolved problem. In recent years, the discovery of Helicopter pylori is a great advance in understanding the cause and treatment of peptic ulcer disease. However, the relationship between psychosocial factors and Helicopter pylori (HP) infection n peptic ulcer disease is still obscured. This study is designed to examine the relationship among peptic ulcer, upper gastrointestinal tract symptoms, psychosocial variable and HP infection. A total of 88 people were recruited in the first year study including people with symptomatic peptic ulcer disease, and asymptomatic non-ulcer individuals. The study of the applicability of the research instruments in this population revealed promising results. Four factors were extracted from the gastrointestinal symptom checklist which explained 52.1% of the total variance. The Cronbach\'s a of the checklist is 0.65. Brief Symptom Rating Scale (BSRS) is a instrument previously used in the evaluation of psychiatric symptoms in primary practice setting. In this study, the Cronbach\'s a of each sub scale was ranged from 0.40 to 0.75. The neurotic sub scale of the Maudsley Personality Inventory (MPI) was 0.79 and the extroversion sub scale was 0.71. More of the symptomatic patients had upper abdominal pain. Ninety-two point five percent of the people with peptic ulcer disease had Helicopter infection compared to 50 percent infection rate among health people.

D.16 完成檢誤日期:1999-12-31
D.17 預定釋出日期:0000-00-00
D.18 初次釋出日期:2000-08-01
D.19_1 最新版釋出日期:2000-08-01
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10.6141/TW-SRDA-E87085-1
https://efenci.srda.sinica.edu.tw/webview/index.jsp?object=https://efenci.srda.sinica.edu.tw:80/obj/fStudy/E87085
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